BE THE NEW

Principal DMPK Scientist

in a biotech company focused on the discovery, design and development of innovative peptide-based medicines

Currently, we are looking for a new principal DMPK scientist, who has experience in supporting discovery and development projects in characterization and selection of drug candidates. If this sounds like you, and you are ready to take on a broad area of responsibilities with an independent attitude, you are a match for us.

The Department of Bioanalysis and Pharmacokinetics consists of a DMPK- and immunogenicity group. As a DMPK principal scientist you will lead the in vitro and in vivo ADME, PK and toxicokinetic efforts to support drug discovery and development. Specifically, the candidate will design, manage, and execute in vitro and in vivo programs both in-house and at contract research organizations. The candidate will also be responsible for analyzing, interpreting, and modeling DMPK and PK/PD data. The candidate will contribute to scientific publications and regulatory submissions as required.

Responsibilities

Design, conduct, and manage in vitro, and in vivo experiments to evaluate the ADME and PK profiles as well as toxicokinetics of drug candidates both in-house and at contract research organizations
Develop and execute assays for measuring drug concentration and metabolite identification from in vitro and in vivo experiments
Champion innovation and new initiatives in discovery programs by proactively reviewing literature and other technological advancements in the scientific area
Interpret and present research data and findings in internal and external scientific meetings and conferences
Contribute effectively to patents, reports, and publications of scientific findings

Candidate profile

Ph.D. in pharmaceutics, or a relevant scientific discipline and experience in bioanalysis and pharmacokinetics from the pharmaceutical industry
Demonstrated knowledge of ADME, PK/PD, and bioanalytical development of small molecules or peptide therapeutics
Experience in LC-MS/MS based bioanalytical techniques including assays for in vitro metabolism and drug-drug interactions
Hands-on experience with developing quantitative and qualitative LC-MS assays to analyze peptide drug candidates preferred
Hands-on experience in NCA, compartmental PK and PK/PD analysis in phoenix WNL preferred
Experience in contributing bioanalysis and ADME parts of regulatory submission preferred
Ability to collaborate with interdisciplinary team with excellent written and oral communication skills
Ability to multi-task to meet research and development goals
Drive to solve problems and ability to work independently

Bonding to innovate 

Our employees are fundamental to our success, and we continue to be able to attract and retain people with vast experience and talent. We have a unique culture, characterized by excellent teamwork and strong engagement across the organization.

Making bonds is at the core of everything we do. From discovering and developing the best new peptide drugs for patients, to engaging with our partners or connecting with each other.

We bond as a result of our entrepreneurial culture where our people are encouraged to pursue their ideas and turn them into reality. We are curious about each other’s knowledge and expertise.

We bond through curiosity and playfulness as a team, allowing ourselves to challenge common thinking and drive future innovation. Zealand Pharma is a place where everyone is heard and contributes to the success, we all want to experience.

The Zealand Pharma DNA builds on four values: (1) We are bold, (2) We empower people, (3) We work as one team, and (4) We can be trusted.

Let’s bond and be bold 

We offer a combined compensation package which includes a base salary, pension, bonus, and a possibility to join our employee share program. We care about our employees’ well-being and offer health insurance, use of massage, fitness, and a range of social clubs and activities

To find out more about working at Zealand, visit https://www.zealandpharma.com/careers/zealand-as-a-workplace/

Interested? Please apply no later than May 10, 2024, or as soon as possible. The applications will be reviewed as they come in.

For further information, please contact Senior Director, Carsten Boye Knudsen on cknudsen@zealandpharma.com.

About Zealand Pharma A/S

Zealand Pharma A/S (Nasdaq Copenhagen: ZEAL) ("Zealand") is a Danish biotechnology company on a mission to change lives with next generation peptide medicines. In our effort to reach our goals bonding is at the core of everything we do. Let it be discovering and developing the best new peptide drugs for patients, engaging with partners or connecting with each other. This has led to more than 10 drug candidates invented by Zealand having advanced into clinical development, of which two have reached the market. Zealand’s current pipeline of internal product candidates focus on specialty gastrointestinal and metabolic diseases. Additionally, the portfolio includes clinical license collaboration with Boehringer Ingelheim and pre-clinical license collaboration with Alexion Pharmaceuticals. Zealand is based in Copenhagen (Søborg), Denmark. For further information about the Company's business and activities, please visit www.zealandpharma.com or bond with us through LinkedIn or Twitter @ZealandPharma.